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From a mini centrifuge for Eppendorf tubes to a superspeed floor model at 100,000 x g: which centrifuge fits your sample type, volume and protocol? This guide takes you quickly to the right type and rotor.
The choice always starts with your sample type, the volume required per run and the maximum g-force (RCF). Identify your situation and go straight to the right range.
Compact spin-downs of Eppendorf and PCR tubes. Fast, small and ideal for the bench.
View mini centrifuges →
High g-force for 1.5/2 ml tubes, with or without cooling. For DNA/RNA isolation and pelleting.
View microcentrifuges →
Versatile benchtop models (C/X/S Series) for blood tubes, cell culture and routine, up to 30,279 x g. CE-IVD option.
View benchtop centrifuges →R models with constant rotor temperature (-10 to +40 °C) for temperature-sensitive samples such as proteins, enzymes and RNA.
View refrigerated centrifuges →
Floor models (LYNX, BIOS) for protein purification, virus isolation, cell fractionation and bioprocessing up to 16 litres.
View superspeed →
Cryofuge 8 and 16, specifically certified for blood bank and transfusion applications with high capacity and cooling.
View blood bank →Not sure which type or rotor fits your protocol? Request free advice. We advise based on your g-force, volume and sample type.
By spinning samples at high speed, components are separated by density: heavier particles move outward, lighter ones stay on top. The distinction between centrifuge types lies in three core parameters: the maximum g-force (RCF), the volume per run and the available rotor types.
Always use RCF (x g), not RPM. RPM is rotor-dependent and not comparable between centrifuges or rotors; protocols written in RPM are not reproducible on other equipment. RCF accounts for the rotor radius and reflects the actual force on your sample. All Thermo Scientific centrifuges convert automatically based on the selected rotor.
Routine blood separation and urine sediment: 300 to 3,000 x g. Cell biology and molecular biology: 5,000 to 30,000 x g. Purification of proteins, viruses and subcellular organelles: superspeed centrifugation above 30,000 x g. For temperature-sensitive samples, a refrigerated (R) model is always the safest choice.
The rotor type determines the quality of your separation and its suitability for your application.
Four factors determine which centrifuge suits you.
Blood separation and urine sediment: 300 to 3,000 x g. Cell biology: 5,000 to 20,000 x g. Protein and virus isolation: up to 100,000+ x g. Expressed in RCF, not RPM.
From 12 x 2 ml (mini centrifuge) to 4 litres (high-capacity benchtop) and 16 litres (BIOS floor centrifuge). Do not underestimate the capacity you need.
Temperature-sensitive samples require a refrigerated R model. Choose fixed-angle for pelleting and speed, swing-out for clinical and gradient separation.
For patient diagnostics, a CE-IVD model (IVDR 2017/746) is mandatory. Choose a benchtop or floor model based on available space and throughput.
Identify your situation and see which type fits your application.
RPM (revolutions per minute) indicates the rotation speed but does not account for the rotor radius. RCF (x g) is the actual force on your sample and the only unit comparable between different centrifuges and rotors. Always use RCF in your protocols for reproducible results.
A fixed-angle rotor suits pelleting, differential centrifugation and molecular biology where speed and high g-forces matter. A swing-out rotor is better for clinical analyses (urine sediment, blood separation), density gradient centrifugation and applications where the pellet must be assessed visually or removed carefully.
Choose a refrigerated R model when your samples are temperature-sensitive: proteins, enzymes, RNA, live cells and other biological samples that degrade with a temperature rise. Non-refrigerated models are cheaper but limited in use. When in doubt, a refrigerated model is the safest choice.
CE-IVD certification is mandatory under the IVD Regulation (IVDR 2017/746) for centrifuges used for in-vitro diagnostic testing of patient material. The Cryofuge and the C/X/S Series are available as certified IVD-MD variants. Always check before purchase that the correct model is ordered.
Yes. Poly Temp Scientific services centrifuges of all brands, including Eppendorf, Beckman Coulter, Hettich and Sigma. The contract covers visual and functional inspection, electrical testing, RPM calibration, rotor inspection with lifetime registration and cleaning.
From mini centrifuge to superspeed floor model: our specialists advise you on the type that fits your g-force, volume, rotor type and compliance requirements.
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