Refrigerators and freezers 7 April 2026 2 min read

Cleanroom compatible freezers: TSX 12 cu ft under ISO 14644-14

In cleanrooms, particle control is essential. Therefore, equipment should match the required class with evidence. This declaration explains how a compact TSX family was evaluated. Moreover, it states which unit represented worst-case testing. This helps you justify choices to QA and audits.

Poly Temp editorial

Laboratory equipment specialists

Table of contents

1Cleanroom compatible freezers and ISO 14644-14
2Cleanroom compatible freezers: ISO Class 5 and EU GMP Grade A
3One size, multiple temperatures, and five voltage options
4Airflow and moving parts: where particles may be driven out

Cleanroom compatible freezers and ISO 14644-14

Cleanroom compatible freezers are assessed for suitability in controlled environments. Therefore, this document describes an internal evaluation and the selection of representative samples for third-party environmental testing. Next, the product family is identified as “TSX1204”. The grouping is supported by engineering justification and worst-case family representation. As a result, one tested unit can support conclusions for the broader family, within the scope of airborne particle cleanliness.

Cleanroom compatible freezers: ISO Class 5 and EU GMP Grade A

The representative unit TSX1204BD was tested to ISO 14644-14. This part of ISO 14644 provides a method to assess equipment suitability for cleanrooms, focused on airborne particle cleanliness as specified in ISO 14644-1. Moreover, the declaration states suitability for ISO Class 5.0 “In Operation” for 0.1 μm to 5.0 μm. Therefore, this matters for high-criticality areas and stringent workflows. Finally, service and maintenance supports stable performance, alongside preventive maintenance.

One size, multiple temperatures, and five voltage options

This family includes one unit size with an internal capacity of about 12 cu ft. Moreover, it covers three operating temperatures: +4°C, +5°C, and -30°C. Therefore, the declaration notes there are no significant design differences that impact cleanroom compatibility. Next, five voltage options are available without changing compatibility, because airflow remains the same. As a result, you can select electrical configurations to match your site, while keeping a clear link to laboratory freezers.

Airflow and moving parts: where particles may be driven out

With UL guidance, two factors were considered: moving parts that may create particles, and airflow that may drive particles outside the unit. The only moving part outside the refrigerated compartment that interacts with the environment is a cooling fan. Next, air is pulled through the condenser and exits via vent holes at the top. This occurs in the Compressor Deck Area, where active airflow is present. As a result, airflow direction, fan size, and fan speeds are consistent across models, supported by laboratory refrigerators and the brand page Thermo Scientific.