The Thermo Scientific Microliter 48×2 sealed fixed-angle rotor is an aluminium rotor for 48 x 2 mL microtubes on the X4 and S4 Series centrifuges. Moreover, this rotor offers a 45 degree angle for optimally consolidated pellet formation. In addition, the Microliter 48×2 reaches a maximum speed of 15,200 rpm and an RCF of 25,314 x g. As a result, you process 48 microtubes per run at superspeed level in a benchtop configuration.
Furthermore, the Microliter 48×2 stands out with its aluminium construction and integrated biocontainment. Therefore, this rotor is the highest-capacity microtube rotor in its class. Moreover, this rotor delivers the highest RCF of all 48-position microtube rotors for the X4 and S4 Series. Additionally, the 45 degree design promotes centralised pellet formation at the bottom of the tube.
In addition, the Microliter 48×2 accommodates standard 1.5/2 mL microtubes directly in the cavity. Subsequently, you process smaller tube formats via dedicated adapters. Moreover, this rotor offers adapter sets for 0.5 mL microtubes, 0.25 mL microtubes and 0.2 mL PCR tubes. As a result, you combine high-throughput processing with flexible microtube protocols.
Finally, the Microliter 48×2 is ideal for molecular biology routine, DNA and RNA isolation and spin column protocols. Therefore, this rotor is the standard choice for laboratories with high-volume microtube applications. As a result, you combine biocontainment with maximum throughput in a single rotor.
| Feature | Microliter 48×2 sealed fixed-angle rotor |
|---|---|
| Rotor type | Fixed-angle, aluminium, sealed |
| Angle | 45 degrees (consolidated pellet design) |
| Maximum capacity | 48 x 2 mL microtubes |
| Maximum speed | 15,200 rpm |
| Maximum RCF | 25,314 x g |
| Maximum rotor radius (Rmax) | 98 mm |
| Compatible centrifuges | X4T, X4TR, X4FR, S4T, S4TR, S4FR |
| Biocontainment | Integrated (sealed configuration) |
| Maximum tube dimensions | 11 x 50 mm |
| Material | Aluminium |
| Suitable for | 1.5/2 mL microtubes (direct), 0.2-0.5 mL tubes (via adapter) |
| Application | Molecular biology, DNA/RNA isolation, spin columns, PCR preparation |
| Delivery | Complete as sealed rotor, adapters sold separately |
| SKU | Description |
|---|---|
| 75003602 | Microliter 48×2 sealed aluminium fixed-angle rotor |
| 75003349 | Replacement O-Ring kit for Microliter 48×2 |
| SKU | Adapter (set of 30) | Capacity | Max. tube dimensions (Ø x L, mm) |
|---|---|---|---|
| 75005753 | 0.5 mL microtube | 48 x 0.5 mL | 8 x 44 |
| 75005754 | 0.25 mL microtube | 48 x 0.25 mL | 6 x 46 |
| 75005752 | 0.2 mL PCR tube | 48 x 0.2 mL | 5 x 20 |
Aluminium fixed-angle rotor with integrated biocontainment for 48 x 2 mL microtubes on the Thermo Scientific X4 and S4 Series centrifuges. With a 45 degree angle and 25,314 x g RCF, the Microliter 48×2 offers the highest capacity in its class. Equipped with adapters for 0.5 mL, 0.25 mL and 0.2 mL PCR tubes. Ideal for molecular biology, DNA/RNA isolation and spin column protocols.








The Microliter 48×2 sealed rotor is compatible with the Sorvall X4T, X4TR, X4FR, S4T, S4TR and S4FR centrifuges. Moreover, this rotor reaches a maximum speed of 15,200 rpm on all compatible models. In addition, all models share the same RCF of 25,314 x g. As a result, the Microliter 48×2 delivers consistent performance across the entire X4 and S4 platform.
The Microliter 48×2 has a 45 degree angle for optimally consolidated pellet formation. Moreover, pellets form better at the bottom of the microtube at a steeper angle. In addition, this angle improves the separation between pellet and supernatant. As a result, you remove the supernatant more easily without pellet loss, which is ideal for DNA and RNA isolation and protein pelleting.
The Microliter 48×2 accommodates standard 1.5/2 mL microtubes directly in the cavity. Moreover, this rotor offers maximum tube dimensions of 11 x 50 mm. In addition, you process 48 microtubes per run, the highest capacity in its class. As a result, this rotor is ideal for high-throughput molecular biology routine.
For the Microliter 48×2, three adapter sets are available for smaller tube formats. Moreover, the 0.5 mL microtube adapter set (SKU 75005753, set of 30) is available for lower volumes. In addition, Thermo Scientific offers the 0.25 mL microtube adapter (SKU 75005754) for very small volumes. Furthermore, a 0.2 mL PCR tube adapter (SKU 75005752) is available for PCR sample preparation.
The Microliter 48×2 has an aluminium construction and reaches 25,314 x g, whereas the Fiberlite F21-48×2 is a carbon fiber rotor with 25,055 x g. Moreover, both rotors reach the same 15,200 rpm on the X4 and S4 platform. Conversely, the Fiberlite F21-48×2 is lighter in handling. Therefore, choose the aluminium Microliter 48×2 for solid reliability and the Fiberlite F21-48×2 for ergonomics.
The Microliter 48×2 is highly suitable for high-throughput molecular biology applications. Moreover, this rotor is the standard choice for DNA and RNA isolation via spin column protocols. In addition, this rotor accommodates PCR sample preparation and protein precipitation. Furthermore, this rotor is suitable for cellular fractionation and filtration tube workflows.