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The Savant SpeedVac SPD130DLX modular vacuum concentrator from Thermo Scientific is a compact deluxe benchtop concentrator for drying aggressive and volatile solvents. Unlike the SPD120, the SPD130DLX features a heated glass lid with radiant lamps, a built-in digital vacuum gauge and vacuum-based run that automatically stops the cycle at a preset vacuum level. As a result, this model is ideal for combinatorial chemistry and broader solvent applications.
Firstly, the SPD130DLX is specifically developed for combinatorial chemistry and applications with aggressive solvents. Therefore, this model features TEFLON components throughout the entire vapor path and a dual valve manifold that minimizes exposure to solvent vapor. In addition, the dedicated bleed port ensures unidirectional vapor flow. As a result, the SPD130DLX achieves ultimate chemical resistance against aggressive and volatile solvents.
Firstly, the most important difference with the SPD120 is the heated glass lid with radiant lamps. Subsequently, these lamps radiate heat directly onto the samples. As a result, evaporation speed is significantly increased. In addition, you switch the radiant heat on and off manually with the RL On/Off button during a run. However, when processing microplates you deactivate the radiant heat to prevent deformation.
Firstly, a second distinguishing feature is the built-in digital vacuum gauge. As a result, you monitor the vacuum level continuously without external measuring equipment. Moreover, the gauge is adjustable from 20 to 0.1 Torr in 0.1 Torr increments. In addition, both Torr and milliTorr units are displayed. Finally, atmospheric pressure is shown as “HPr” for clear status information.
Firstly, the SPD130DLX offers two run types: Time-based and Vacuum-based. With Vacuum-based, the run stops automatically when the preset vacuum level is reached. As a result, you guarantee consistent drying without over- or under-evaporation, regardless of batch variation. Subsequently, results are reproducible for every run. Therefore, this is ideal for GMP and GLP applications.
Firstly, the SPD130DLX is supplied as a standalone concentrator unit. As a result, you choose which cold trap and which vacuum pump best matches your lab. Moreover, you combine the SPD130DLX with a UVS850DDA Universal Vacuum System for a Semi-Integrated setup with ANT100 post-trap. Alternatively, you pair it with a standalone RVT450 cold trap plus VLP120 vacuum pump, DVG50 vacuum gauge and VPOF110 oil filter for a Component High Vacuum System.
Firstly, the SPD130DLX accepts a considerably broader range of solvents than the SPD120. For example, acetone, chloroform, DCM (dichloromethane), cyclohexane, ethyl ether and petroleum ether. In addition, the system works with standard non-aggressive solvents such as water, acetonitrile, methanol, ethanol, isopropanol and ammonium hydroxide. Finally, low concentrations of acid such as 0.1% TFA, 0.1% acetic acid and 1% formic acid are also suitable.
Firstly, the SPD130DLX offers 3 preset programs plus 3 user-defined programs, 6 in total compared to 3 on the SPD120. The preset programs are pre-configured for Water (45°C, vacuum-based at 1.0 Torr), Low Boiling ACN/MEOH (65°C, time-based, 100 mTorr) and HPLC (no heating, time-based, 100 mTorr). Furthermore, the user-defined programs are fully customizable and storable for your own applications.
Firstly, the SPD130DLX exports live run data every minute via the USB type A/B port on the rear of the unit. Subsequently, you receive chamber temperature, remaining heat time, run time and vacuum value in CSV format at 115200 baud. As a result, you have more comprehensive data than with the SPD120 for GMP and GLP reporting.
Firstly, the glass lid with safety interlock locks automatically during a run. Consequently, the lid opens only when the rotor has fully stopped. In addition, the SPD130DLX features a lid-stay mechanism that holds the lid in the open position. Finally, an emergency cover release allows sample removal during a power failure.
Firstly, the SPD130DLX is available in two configurations. The first is the standalone concentrator unit with TEFLON tubing (1/2″ I.D. × 90 cm). Secondly, the P1 kit with additional accessories for immediate use. In addition, for a complete Component High Vacuum setup you order separately the RVT450 or RVT5105 cold trap, VLP120 vacuum pump, DVG50 vacuum gauge, VPOF110 oil filter and a suitable rotor.
Firstly, the SPD130DLX is used in combinatorial chemistry, medicinal chemistry, drug discovery, organic synthesis, life sciences and the pharmaceutical industry. Typical applications include drying organic synthesis products, peptide synthesis, library purification, HPLC fractions with aggressive solvents and residue analysis. Would you like advice on the right SpeedVac for your application? Contact us and our product specialists will be glad to help.
| Property | Value |
|---|---|
| Model | SPD130DLX-230 |
| System type | Modular deluxe (concentrator unit, cold trap and pump separate) |
| Capacity | Up to 120 × 1.5-2.0 mL microtubes (RH120-11 rotor), or 6 × 50 mL conical tubes (RH6-50) |
| Dimensions (W × D × H) | 36 × 46 × 36 cm |
| Weight | 28 kg |
| Chamber material | TEFLON-coated chemical resistant aluminum casting |
| Vapor path materials | TEFLON and TEFLON-coated materials (exclusively in vapor path) |
| Cover | Heated glass cover with radiant lamps and safety interlock |
| Dual valve manifold | Yes (for minimal vapor exposure) |
| Lid-stay mechanism | Yes |
| Temperature range | 35-80°C in 5°C increments, or “no” for no heating |
| Pre-heat function | 45°C |
| Vacuum level setting | 20 to 0.1 Torr in 0.1 increments |
| Vacuum gauge | Built-in digital vacuum gauge (Torr and milliTorr) |
| Run types | Time-based and Vacuum-based |
| Programs | 3 preset (Water, Low Boiling ACN/MEOH, HPLC) + 3 user-defined (modifiable and storable) |
| Timer range | 2 independent timers: 1 minute to 9 hours 59 minutes, or continuous (CCC) for heat time |
| Operating modes | Auto Run, Manual Run, Pre-heat, RL On/Off (radiant lamp) |
| Data export | USB type A/B port, 115200 baud, CSV format (temperature, heat time, run time, vacuum pressure) |
| Power supply | 230 VAC / 50 Hz, 3 amperes |
| Fuse | 3 A, 250 VAC, Time-lag |
| Induction motor | Maintenance-free |
| Compatible solvents | Water, acetonitrile, acetone, acetic acid, ammonium hydroxide, n-butanol, chloroform, cyclohexane, DCM, ethyl acetate, ethanol, ethyl ether, n-hexane, n-heptane, isopropanol, isobutanol, methanol, petroleum ether, n-propanol, pyridine, 0.1% acetic acid, 0.1% TFA, water+ACN+MeOH+1% formic acid |
| Audible notifications | Yes (5 beeps startup, 1 beep run start, 3 beeps stop, error tones) |
| Emergency cover release | Yes |
| Maximum altitude | 2000 meters above sea level |
| Ambient temperature | 17°C to 32°C |
| Humidity | 20% to 80% non-condensing |
| Required ventilation space | 10 cm (4 inch) on all sides, 46 cm (18 inch) overhead for cover opening |
| Included (standard) | SPD130DLX concentrator, TEFLON tubing (1/2″ I.D. × 90 cm), power cord |
| Recommended additions | Cold trap (RVT450, RVT5105 or UVS850DDA) and vacuum pump (VLP120 or similar) |
Deluxe modular SpeedVac vacuum concentrator for combinatorial chemistry and aggressive solvents. Compact benchtop concentrator unit with heated glass lid, radiant lamps and built-in digital vacuum gauge. Medium capacity up to 120 microtubes, vacuum-based run for reproducible drying, 6 programs and comprehensive USB data export. Available as standalone unit or P1 kit with accessories.
The SPD130DLX is used for combinatorial chemistry, organic synthesis, drug discovery and concentrating samples in aggressive organic solvents. Typical applications include drying synthesis products, peptide synthesis, library purification, HPLC fractions with aggressive solvents and residue analysis.
Both are modular medium capacity SpeedVacs with the same dimensions and capacity. However, the main difference is the deluxe execution of the SPD130DLX. Firstly, the SPD130DLX features a heated glass lid with radiant lamps for faster evaporation. Secondly, it has a built-in digital vacuum gauge and vacuum-based run that automatically stops the cycle at a preset vacuum level. Finally, the SPD130DLX accepts broader solvents such as acetone, chloroform, DCM and cyclohexane, which the SPD120 cannot process.
The SPD130DLX accepts a broad range of solvents, including aggressive organic solvents. For example, acetone, chloroform, DCM (dichloromethane), cyclohexane, ethyl ether, petroleum ether, acetonitrile, methanol, ethanol, isopropanol, n-hexane, n-heptane, ethyl acetate, pyridine and ammonium hydroxide. In addition, the system works with low concentrations of acid such as 0.1% TFA, 0.1% acetic acid and 1% formic acid. However, for strong acids and bases or even more aggressive solvents you choose the SPD140DDA or SPD300DDA.
You choose between three recommended options. Firstly, the RVT450 (cooling to -50°C, suitable for most solvents). Secondly, the RVT5105 (cooling to -105°C, for lyophilization and low-boiling solvents). Thirdly, the UVS850DDA Universal Vacuum System (integrated cold trap and pump, with ANT100 post-trap for oligonucleotide applications).
Both contain the same SPD130DLX concentrator unit. The SPD130DLX-230 is the standalone unit with TEFLON tubing (90 cm). The SPD130P1-230 is a kit with additional accessories such as rotor, CryoCool heat transfer fluid and condensation flask, ready for immediate use. For the specific kit components, our product specialists are happy to assist.
Vacuum-based run is an automatic run mode that stops the cycle as soon as the preset vacuum level is reached. As a result, you guarantee consistent drying between runs, regardless of batch variation or sample volume. Subsequently, results are reproducible for GMP and GLP applications. By contrast, the SPD120 does not have this function and stops only on a time basis.
Yes, via the USB type A/B port you export live run data at a fixed baud rate of 115200. Every minute, you receive the live chamber temperature, remaining heat time, run time and vacuum value in CSV format. As a result, you have more comprehensive data than with the SPD120 for GMP and GLP reporting.
The SPD130DLX offers 3 preset programs and 3 user-defined programs. The preset programs are: Water (45°C, vacuum-based at 1.0 Torr, 2 hours), Low Boiling ACN/MEOH (65°C, time-based, 100 mTorr, 2 hours) and HPLC (no heating, time-based, 100 mTorr, 2 hours). In addition, you configure 3 of your own programs with all parameters fully customizable.
No, radiant heat should not be used with microplates. As a result, they may melt or deform. For microplate applications you switch off the RL On/Off button and use only chamber heat up to a maximum of 80°C.
230 VAC / 50 Hz, 3 amperes. The plug is a SCHUKO standard European plug and fits directly into Dutch wall sockets. The fuse is a 3 A, 250 VAC time-lag fuse.
Yes, with dimensions of 36 × 46 × 36 cm and a weight of 28 kg, the SPD130DLX fits on a standard laboratory benchtop. A clearance of 10 cm on all sides is required for ventilation, with 46 cm overhead for opening the cover.
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