UVS850DDA universal vacuum system with VaporNet for aggressive solvents

The UVS850DDA is an integrated universal vacuum system from Thermo Scientific that combines a three-stage oil-free pump, a refrigerated cold trap and a post-trap in a single compact unit. Firstly, the system is specifically engineered for processing volatile and aggressive solvents such as methylene chloride and trifluoroacetic acid, typically used during the synthesis phase of combinatorial drug discovery. Secondly, the three-stage diaphragm pump delivers a maximum vacuum of <0.6 torr (0.8 mbar), significantly stronger than standard universal vacuum systems. Moreover, PTFE-coated valves and PTFE tubing in the vapor path provide maximum corrosion resistance.

Three-stage high-efficiency pump for strong vacuum

Firstly, the UVS850DDA features a three-stage oil-free diaphragm pump with a displacement of 36 L/min at 60 Hz or 30 L/min at 50 Hz. In addition, the system reaches a maximum vacuum of <0.6 torr (0.8 mbar), which creates optimum evaporation conditions for aggressive and high-boiling solvents. Furthermore, the oil-free design prevents aggressive vapors from degrading pump oil, which is a frequent maintenance issue with oil-sealed pumps. As a result, the pump delivers reliable vacuum without routine maintenance.

VaporNet technology for >95% solvent recovery

Firstly, the UVS850DDA combines a single-stage refrigerated vapor trap (-50°C) with the patented VaporNet Controller. In addition, VaporNet modulates the vacuum flow, which causes solvent molecules to remain in the cold trap longer than would be possible with a constant vacuum. Moreover, this combination results in greater than 95% recovery of methylene chloride and organic solvent mixtures. As a result, you activate VaporNet via a switch in the VOLATILE position for low-boiling solvents (boiling point <95°C) or set it to AQUEOUS for water-based solutions and high-boiling solvents.

Integrated ANT100 post-trap as standard

Firstly, the UVS850DDA ships standard with the ANT100 post-trap that captures and neutralizes acid vapors in the pump exhaust. Secondly, you attach the post-trap via a slide-on bracket on the right side of the unit. In addition, an ammonia neutralizing solution (ANS121) is available as a consumable for the ANT100 when processing ammonium hydroxide or similar basic substances. Furthermore, you order a suitable acid-neutralizing solution separately when handling TFA, HCl or similar acids.

PTFE vapor path for maximum chemical resistance

Firstly, all tubing in the vapor path is made of PTFE, as are the pump valves. In addition, this PTFE coating prevents corrosion and degradation caused by aggressive solvent vapors. Moreover, this design makes the UVS850DDA particularly suitable for processing TFA, methylene chloride, strong acids and bases. As a result, choose the simpler UVS450A when you work exclusively with standard non-aggressive solvents.

Combining with SpeedVac concentrators

Firstly, the UVS850DDA is designed as the integrated vacuum system in modular SpeedVac setups. Secondly, the unit is the standard vacuum source in our P2 kits for the SPD140DDA and SPD300DDA, both designed for aggressive solvents. In addition, you also combine the UVS850DDA with other vacuum-dependent equipment such as vacuum ovens, gel drying systems or rotary evaporators. As a result, the integrated design saves benchtop space (the unit occupies less than 46 cm) compared with separate cold trap and pump setups.

Used in these sectors

• Pharmaceutical industry and biotech: combinatorial drug discovery, peptide synthesis, processing of TFA and strong acids
• Medical diagnostics: concentration of samples in aggressive buffers and solvent mixtures
• Food industry: analysis of complex matrices with aggressive solvents
• Agriculture and horticulture: extraction of plant metabolites using chlorinated solvents
• Academic research: synthetic chemistry, organic chemistry and proteomics workflows

The UVS850DDA vacuum system is available through Poly Temp Scientific, your Dutch partner for Thermo Scientific laboratory equipment with over 40 years of experience. Request a quote via our contact page or browse our complete product range.